Rubrik: Biotechnologie
(Treffer aus pharmind, Nr. 10, Seite 1410 (2019))
Busimi A | Bauert D
Primary Packaging Solutions for Wearable Injectors / Busimi and Bauert • Wearable Injectors · Busimi A, Bauert D ·
1Schott Pharmaceutical Systems, Mainz und Schott Schweiz AG, St. Gallen, Schweiz
The global drug development pipeline is filled with biological drugs and many of them are targeted for personalized medicine [ 1 ]. Despite the superior efficacy and safety, the manufacturing and administration of biological drugs is very expensive and poses many challenges. For many biological drugs, the overall dose and thus protein concentration is quite high and influences drug stability and viscosity, drug processing and device injection forces [ 2 ]. Because of the concentration and viscosity, the majority of these products are injected, in most cases, by intravenous infusion in a hospital setting. Intravenous (IV) administration incurs higher proximal and physical ...