Rubrik: Technik
(Treffer aus pharmind, Nr. 08, Seite 631 (2026))
Antonino P
From Automation to Physical AI / How Digitalization Reshapes Personnel in Pharma 4.0 · Antonino P · Fraunhofer IESE
Pharma 4.0 Physical AI Digitalization Digital twins Simulation Pharmaceutical production is transitioning into the so-called Pharm 4.0, which is a concept shaped and formalized, among others, by the International Society for Pharmaceutical Engineering (ISPE) [ 1 ]. Pharma 4.0 aims at enabling scalable and cost-efficient production of advanced therapies like mRNA-based vaccines, gene therapies, and cell-based treatments, which introduce unprecedented complexity and variability, requiring production systems to adapt dynamically while maintaining strict quality standards. In this regard, Pharma 4.0 production systems are inherently software-intensive, data-driven, and adaptive, forming a connected end-to-end ecosystem across the entire product lifecycle that must operate consistently across ...