Privatsphäre-Einstellungen

Grundlagen von Restricted Access Barrier System RABS/Isolator aus Sicht eines Anlagenplaners

Dipl.-Ing. Eberhard Münch

Carpus Prozess Experten GmbH, Hattersheim/Main (Germany)

Correspondence: Eberhard Münch, Carpus Prozess Experten GmbH, Im Nassauer Hof 3, 66795 Hattersheim/Main (Germany), e-mail: eberhard.muench@carpus.de

Basics of Restricted Access Barrier Systems RABS/Isolators from the Plant Designer’s Point of View

RABS and Isolator are the state of the art technologies for aseptic filling.
At the beginning of the design phase, it is necessary to decide which technology is going to be used, due to the influence for the layout amongst others. This paper introduces and exemplifies the different technologies.
Beside the containment technology the material transfer is also very important for planning and construction. Using the example of rubber stopper transfer the different options are described.
At the end of the paper the different steps for planning and realising a RABS or Isolator are explained.

Key words Aseptische Abfüllung • Isolator • Planungsschritte • RABS • Schleusungsvorgänge • Stopfentransfer