Privatsphäre-Einstellungen

Safe Handling of Highly Potent Compounds in the Pharmaceutical Industry

A pharmaceutical manufacturer is obliged to avoid over exposure of its employees (staff) when dealing with highly potent compounds. Hence a safety concept comprising different safety measures has to be established as a prerequisite for safe handling of highly potent compounds. Initially, acceptance limits have to be determined and compounds are to be classified and assigned to four hazard groups (G1- G4) according to their known pharmacological and toxicological properties. Secondly, process inherent risks are to be evaluated and measures are to be taken to reduce potential risks. Finally, the effectiveness of these measures needs to be assessed.
In contrast to Pharmaceutical Production, Pharmaceutical Development strives for containment solutions which are not only effective with respect to staff protection, but also allow a higher process flexibility. The solutions realized are dependent on the dosage form, the process steps and manufacturing equipment used.