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State of the Art Sanitisation of Purified Water (PFW)
Originale
1. Introduction
2. PFW international specification
3. Water Treatment today – PFW generation and distribution (embedded issues)
4. Supplementary techniques adopted to limit microbial growth and its proliferation
5. Advanced Tank Disinfection Technology by disinfection in place
6. Example of Advanced Tank Disinfection Technology in an API manufacturing unit
7. WFI Feed Water
8. Conclusion
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2. PFW international specification
3. Water Treatment today – PFW generation and distribution (embedded issues)
4. Supplementary techniques adopted to limit microbial growth and its proliferation
5. Advanced Tank Disinfection Technology by disinfection in place
6. Example of Advanced Tank Disinfection Technology in an API manufacturing unit
7. WFI Feed Water
8. Conclusion
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Key words , Pharmaceutical industry , Purified water , Microbiological contamination , UV disinfection of tanks , Quality control , Microfloat
Martin Sörensen1, Paramasivam Satish2, Jürgen Weckenmann1 · 1Enviolet GmbH, Karlsruhe, Germany
· 2Seven Hills International Limited, Halesowen, United Kingdom
· 2Seven Hills International Limited, Halesowen, United Kingdom
Correspondence:
Dr. Martin Sörensen, Enviolet GmbH, Schenkenburgstr. 18, 76135 Karlsruhe, Germany, e-mail: info@enviolet.com
Abstract
This report focuses on sources, proliferation and control of microbiological growth inside a purified water (PFW) tank.
The most widely used practice in the industry for controlling microbiological growth inside tanks and pipework is to operate the PFW system with frequent hot water sanitisation and regular microbiological monitoring to ensure the water being of an appropriate (...)
