Microcrystals & Nanocrystals Produced by Rotor-Stator High Speed Stirring

Rubrik: Originale

(Treffer aus pharmind, Nr. 08, Seite 1196 (2016))

Scholz P | Arntjen A | Keck C

Microcrystals & Nanocrystals Produced by Rotor-Stator High Speed Stirring / Scholz et al. • Microcrystals & Nanocrystals · Scholz P, Arntjen A, Keck C · ¹Applied Pharmacy, University of Applied Sciences Kaiserslautern, Campus Pirmasens, Pirmasens, Germany und ²Department of Pharmaceutics, Biopharmaceutics and NutriCosmetics, Institute of Pharmacy, Freie Universität Berlin, Germany und ³Institute of Pharmaceutics and Biopharmaceutics, Institute of Pharmacy, Philipps-Universität Marburg, Germany
Microcrystals Nanocrystals Suspension Nanosuspension Rotor-stator high speed stirring Rotor-stator systems are widely used for the mixing and crushing or even foaming of different components to obtain homogeneous systems, i. e., solutions, emulsions, suspensions or foams. The applications of this technique are manifold. In the pharmaceutical field rotor-stator systems are often used for the dispersion of particles [ 1 , 2 ]. The aim is to obtain homogenous small-sized suspensions with a narrow size distribution within a short time. Rotor-stator systems consist of a rotating part (the rotor) which rotates while stirring at high speed inside of a stationary part (the stator). ...