Geschlossene Systeme in der Pharmaproduktion Problemanalyse des HAPI-Feststoff-Handling für Pharma-Filtertrockner (Rührdrucknutschen) Torsten Belger Powder Systems Limited (PSL), Liverpool (Großbritannien) Korrespondenz: Torsten Belger, Powder Systems Limited, Estuary Business Park, Liverpool L24 8RG (UK), Closed Systems in Pharmaceutical Production / Analysis of the handling of HAPI solids with filter dryers (Filter Dryer) The article deals with problems relating to solids handling and containment for HAPI Filter Dryers (Highly Active Pharmaceutical Ingredients) in the primary Pharmaceutical Industry. New and validated solutions for dealing with sampling, solids discharge, heel removal, problems with solids handling and cleaning of discharge devices and filter media are addressed. The article also aims to provide ideas for the effective integration of Containment Systems with other machines and applications in the secondary and primary pharmaceutical industries. Key words Containment • Filtertrockner • Glovebox • Isolator • Pharmaproduktion • Probenahme • Rührdrucknutsche |
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pharmind 2006, Nr. 6, Seite 761
