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Sie suchen in allen Bereichen nach dem Autor Ernst J.
In der Rubrik Zeitschriften haben wir 1 Beitrag für Sie gefunden
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MerkenBreaking the Biofilm Barrier
Rubrik: Originale
(Treffer aus pharmind, Nr. 02, Seite 248 (2019))
Ernst J | Klinger-Strobel M | Thamm J | Makarewicz O | Pletz M | Fischer
Breaking the Biofilm Barrier / The Role of Stabilizers in Biofilm Penetration and Pulmonary Antibiotic Delivery by Polymer Nanoparticles · Ernst J, Klinger-Strobel M, Thamm J, Makarewicz O, Pletz M, Fischer< < · 1Pharmaceutical Technology and Biopharmacy, Institute for Pharmacy, Friedrich Schiller University Jena, Jena und Institute for Infectious Diseases and Infection Control, Jena University Hospital, Jena und Jena Center for Soft Matter (JCSM), Friedrich Schiller University Jena, Jena und
nanoparticle stabilizer biofilm Staphylococcus aureus Burkholderia cepacia tobramycin Bacterial biofilms play a key role in many diseases like persistent lung infections or infections of catheters, artificial heart valves, and implants. Pathogenic microbes embedded in the self-produced biofilms benefit from the protective matrix as evidenced by the strongly reduced susceptibility against common antibiotics [ 1 – 3 ]. Especially cystic fibrosis patients suffer from biofilm-associated lung infections because of their unfavorable lung conditions with decreased mucocillary clearance and abnormal thick mucus [ 4 , 5 ]. To overcome the limiting biofilm and mucus barrier, nanoparticles made of poly(lactid-co-glycolic acid) (PLGA) ...
