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Sie suchen in allen Bereichen nach dem Autor Lamprecht A.
In der Rubrik Zeitschriften haben wir 2 Beiträge für Sie gefunden
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MerkenAtmospheric Spray Freeze-Drying
Rubrik: Technik
(Treffer aus pharmind, Nr. 02, Seite 182 (2025))
Rautenberg A | Beutler T | Lamprecht A
Atmospheric Spray Freeze-Drying / A more sustainable lyophilization process · Rautenberg A, Beutler T, Lamprecht A · University of Bonn und GEA Lyophil GmbH und University of Bonn
Spray-freeze-drying Efficiency Sustainability Lyophilisates Powders As industries increasingly prioritize sustainability and energy conservation, also the pharmaceutical sector is focussing on optimizing its processes. In 2022, the manufacture of basic pharmaceutical products and preparations in Germany alone consumed over 3 GWh, excluding broader chemical production [ 1 ]. Drying plays a crucial role in ensuring the physical, chemical, and microbial stability of pharmaceutical products. Many active pharmaceutical ingredients (APIs), especially those derived from biotechnological processes, are highly sensitive to heat. Freeze-drying (FD), also known as lyophilization, has become indispensable due to its gentle handling of thermolabile substances. However, it is also one of ...
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MerkenContinuous Atmospheric Droplet-Stream Freeze-Drying Processes
Rubrik: Originale
(Treffer aus pharmind, Nr. 05, Seite 741 (2016))
Süverkrüp R | Wanning S | Lamprecht A
Continuous Atmospheric Droplet-Stream Freeze-Drying Processes / Development and Laboratory System · Süverkrüp R, Wanning S, Lamprecht A · Rheinische Friedrich-Wilhelms-Universität Bonn
Atmospheric lyophilisation Continuous lyophilisation Droplet stream lyophilisation Spray freeze drying Pulmonary drug delivery Uniform spherical porous particles with geometric diameters ranging from about 30–400 μm can be produced in quantities by droplet stream lyophilisation of aqueous solutions containing about 2–10 % of non-volatile solids. In spite of the small size and low density of the particles, the powders are sufficiently stable for handling and have good flow properties. They are readily dispensed and dosed into containers and can be mixed with other disperse solids. In the low size and concentration range, particles with aerodynamic diameters below 5 μm are suited for the pulmonary ...
