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MerkenSyringe Siliconization
Rubrik: Originale
(Treffer aus pharmind, Nr. 03, Seite 404 (2019))
Tölke T | Rudolf J | Pfuch A | Grünler B
Syringe Siliconization / Alternatives to the bake-on process · Tölke T, Rudolf J, Pfuch A, Grünler B · Innovent e. V., Jena und
Silicone oil (PDMS) Siliconization Syringes Water contact angle Gliding force measurement Pre-filled syringes are widely-used in the delivery of parental drug products. This is due to advantages like accurate dosing, less overfill, decreased risk for contamination and convenience for patients regarding product storage and administration [ 1 , 2 ]. Silicone oil is used as lubricant during the production process of ready-to-use syringes. This coating is necessary to prevent the plunger from sticking to the wall of the syringe and to ensure the functionality of the syringe system. Moreover, the silicone oil acts as hydrophobic agent and supports the complete ...
