Rubrik: Originale
(Treffer aus pharmind, Nr. 11, Seite 1556 (2017))
Sauer A | Schmalz D
Modifying Mini-Tablet Dissolution with Cellulose Ethers / Sauer and Schmalz • Mini-Tablet Dissolution · Sauer A, Schmalz D ·
1Shin-Etsu Pharma & Food Materials Distribution GmbH, Wiesbaden und
2Harke Pharma GmbH, Mühlheim an der Ruhr
Cellulose Ethers Mini-tablets Pediatric Dosage Forms Personalized Medicine In the last twenty years, the development of mini-tablets (defined as tablets smaller than 3 mm) has gained more and more interest. This fact is mirrored by the constantly increasing number of publications on this topic, peaked in 2015 with almost 60 articles ( Fig. 1 ) [ 1 ]. Mini-tablets offer a flexible, yet robust and easy-to-manufacture approach to the requirements of heterogenous patient groups like children or senior citizens as well as patients with swallowing difficulties. Being solid dosage forms, these tablets avoid problems associated with the water content of semi-solid forms (e.g., syrups ...