Rubrik: Originale
(Treffer aus pharmind, Nr. 08, Seite 1072 (2020))
Wewers M[1 2 | Warnke G | Finke J[1 2
Influence of Formulation Parameters on Tablet Surface Properties and Film Coating Adhesion / Wewers et al. • Tablet Surface Properties · Wewers M
1 2, Warnke G3, Finke J1 2 · 1Institute for Particle Technology, Technische Universität Braunschweig, Braunschweig; und 2Centre of Pharmaceutical Engineering (PVZ), Technische Universität Braunschweig, Braunschweig und 3JRS Pharma GmbH & Co. KG, Rosenberg
Film coating Lubricants Disintegrants Film Coating Adhesion Cohesive and adhesive failure Tablets are the most common dosage form in pharmaceutical industry. However, they are often further processed to coated tablets by application of one or more layers of mixtures consisting of a film-forming material and several functional excipients. The intention of this can be as versatile as the formulation itself. The film-coating can, for instance, fulfil protective functions. These can be related to the protection of the original dosage form against harmful influences, or the patient by increasing the pharmaceutical drug safety of the final product. Furthermore, the compliance of ...